WHAT IS OZEMPIC BUTT?
- Heather Newman
- Oct 4, 2024
- 2 min read

SHORT ANSWER: YES! YES IT DOES.
Ozempic is a weight-loss drug that can cause a side effect called "Ozempic butt" or "Wegovy butt". This side effect is characterized by a loss of volume and sagging skin in the buttocks, which can make the area appear deflated
Ozempic butt occurs when the body loses fat too quickly, and the skin doesn't have time to adjust. This can lead to excess skin that hangs down, or a generally deflated appearance. Factors that can contribute to the severity of Ozempic butt include:
Amount of weight lost: The more weight lost, the more likely the skin will sag.
Speed of weight loss: Rapid weight loss is more likely to cause sagging skin than gradual weight loss.
Age: Older people may have less skin elasticity and are more likely to develop sagging skin.
Genetics: Some people may be genetically predisposed to having loose skin.
Surgical options like a butt lift can remove excess skin and tighten the area. Minimally invasive treatments like Renuvion or RF Microneedling can also help with skin laxity.
Ozempic (semaglutide), a medication used for treating type 2 diabetes and weight management, works by mimicking a hormone called GLP-1 (glucagon-like peptide-1), which regulates blood sugar and appetite. While it is effective for weight loss, some studies suggest that it can cause not only fat loss but also muscle loss.
Here’s how Ozempic might contribute to muscle loss:
1. Rapid Weight Loss: Significant weight loss, especially rapid loss, can lead to a decrease in both fat and lean muscle mass. Without a proper balance of protein intake and resistance exercise, the body may break down muscle for energy during weight loss.
2. Caloric Deficit: Ozempic reduces appetite, which can lead to consuming fewer calories. If someone is in a prolonged caloric deficit, the body may not have enough nutrients to maintain muscle mass, leading to muscle breakdown.
3. Lack of Exercise: Weight loss from medication alone, without incorporating resistance or strength training, often results in a loss of both fat and muscle. Exercise, particularly strength training, is crucial to preserving muscle mass during weight loss.
4. Age-Related Muscle Loss: Older adults taking Ozempic may be more susceptible to muscle loss since muscle mass naturally declines with age, especially when weight loss occurs without targeted muscle-preserving strategies.
To prevent or minimize muscle loss while using Ozempic, it’s important to maintain a balanced diet with adequate protein intake and engage in resistance training or weight-bearing exercises. Consulting a healthcare provider or nutritionist for a tailored plan is also beneficial.
This is for informational purposes only. For medical advice or diagnosis, consult a professional.
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